Now a large study undertaken by the University of Exeter and University College London and published in the International Journal of Epidemiology suggests that the problem isn’t sitting, it’s not getting enough exercise, and that standing (which may be more comfortable for some people in any event) doesn’t help — though treadmill desks and bike desks would presumably make some kind of difference.
I stood up for a year at my desk, and stopped when my feet started to hurt. After three days, the pain went away. Now I try to take four or five 10 to 30 minute walks every day. Which reminds me… time for a walk!